{"product_id":"cystorelin-injection","title":"Cystorelin Injection","description":"\u003cdiv\u003e\u003c\/div\u003e \u003cdiv\u003e\u003c\/div\u003e \u003cdiv\u003e\u003c\/div\u003e \u003cdiv\u003e\n\u003cspan style=\"font-weight: bold;\"\u003ePrescription items are \u003c\/span\u003e \u003cspan style=\"color: red; font-weight: bold; text-decoration-line: underline;\"\u003eNON-RETURNABLE\u003c\/span\u003e \u003cspan style=\"font-weight: bold;\"\u003e and \u003c\/span\u003e \u003cspan style=\"color: red; font-weight: bold; text-decoration-line: underline;\"\u003eNON REFUNDABLE\u003c\/span\u003e\n\u003c\/div\u003e \u003cdiv\u003e \u003c\/div\u003e \u003cdiv\u003e\u003cstrong\u003eCystorelin Injection expiration date 5\/2021.\u003c\/strong\u003e\u003c\/div\u003e \u003cp\u003eCYSTORELIN\u003csup\u003e®\u003c\/sup\u003e is indicated for the treatment of ovarian follicular cysts in dairy cattle. Ovarian cysts are non-ovulated follicles with incomplete luteinization which result in nymphomania or irregular estrus.\u003c\/p\u003e \u003cdiv\u003eHistorically, cystic ovaries have responded to an exogenous source of luteinizing hormone (LH) such as human chorionic gonadotropin. CYSTORELIN\u003csup\u003e®\u003c\/sup\u003e initiates release of endogenous LH to cause ovulation and luteinization.\u003c\/div\u003e \u003cdiv\u003e \u003c\/div\u003e \u003cdiv\u003eThe recommended intravenous or intramuscular dosage of CYSTORELIN\u003csup\u003e®\u003c\/sup\u003e is 100 mcg (2 mL) per cow.\u003c\/div\u003e \u003cdiv\u003e \u003c\/div\u003e \u003cdiv\u003eIngredients:\u003c\/div\u003e \u003cdiv\u003e \u003cp\u003eEach mL of CYSTORELIN\u003csup\u003e®\u003c\/sup\u003e contains:\u003cbr\u003e \u003c\/p\u003e\n\u003ctable style=\"border-image: initial;\"\u003e \u003ctbody\u003e \u003ctr\u003e \u003ctd style=\"border-image: initial;\"\u003eGonadorelin diacetate tetrahydrate\u003c\/td\u003e \u003ctd style=\"border-image: initial;\"\u003e50 mcg\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"border-image: initial;\"\u003eBenzyl Alcohol\u003c\/td\u003e \u003ctd style=\"border-image: initial;\"\u003e9 mg\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"border-image: initial;\"\u003eSodium Chloride\u003c\/td\u003e \u003ctd style=\"border-image: initial;\"\u003e7.47 mg\u003c\/td\u003e \u003c\/tr\u003e \u003ctr\u003e \u003ctd style=\"border-image: initial;\"\u003eWater for Injection, U.S.P.\u003c\/td\u003e \u003ctd style=\"border-image: initial;\"\u003eq.s.\u003c\/td\u003e \u003c\/tr\u003e \u003c\/tbody\u003e \u003c\/table\u003e pH adjusted with potassium phosphate (monobasic and dibasic). \u003c\/div\u003e \u003cdiv\u003e \u003cp\u003eStorage:\u003cbr\u003e \u003c\/p\u003e \u003cp\u003eKeep at or below 77°f, a brief excursion to 86°f permitted.\u003c\/p\u003e \u003cp\u003eDiscard Remaining Product 90 Days After First Use.\u003c\/p\u003e \u003cp\u003eEndogenous gonadorelin is synthesized and\/or released from the hypothalamus during various stages of the bovine estrus cycle following appropriate neurogenic stimuli. It passes via the hypophyseal portal vessels, to the anterior pituitary to effect the release of gonadotropins (e.g. LH, FSH). Synthetic gonadorelin administered intravenously or intramuscularly also causes the release of endogenous LH or FSH from the anterior pituitary.\u003c\/p\u003e \u003cp\u003eGonadorelin diacetate tetrahydrate has been shown to be safe. The LD50 for mice and rats is greater than 60 mg\/kg, and for dogs, greater than 600 mcg\/kg, respectively. No untoward effects were noted among rats or dogs administered 120 mcg\/kg\/day or 72 mcg\/kg\/day intravenously for 15 days.\u003c\/p\u003e \u003cp\u003eIt has no adverse effects on heart rate, blood pressure, or EKG to unanesthetized dogs at 60 mcg\/kg. In anesthetized dogs, it did not produce depression of myocardial or system hemodynamics or adversely affect coronary oxygen supply or myocardial oxygen requirements.\u003c\/p\u003e \u003cp\u003eThe intravenous administration of 60 mcg\/kg\/day of gonadorelin diacetate tetrahydrate to pregnant rats and rabbits during organogenesis did not cause embryotoxic or teratogenic effects.\u003c\/p\u003e \u003cp\u003eThe intramuscular administration of 1000 mcg to normally cycling dairy cattle had no effect on hematology or blood chemistry.\u003c\/p\u003e \u003cp\u003eFurther, CYSTORELIN\u003csup\u003e®\u003c\/sup\u003e does not cause irritation at the site of intramuscular administration in dogs. The dosage administered was 72 mcg\/kg\/day for seven (7) days.\u003c\/p\u003e \u003c\/div\u003e","brand":"Cystoreline","offers":[{"title":"30mil","offer_id":42834526339160,"sku":"P00900 15 30","price":48.85,"currency_code":"USD","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0604\/1904\/7512\/files\/TP00900.jpg?v=1740100479","url":"https:\/\/www.petsupplies.com\/products\/cystorelin-injection","provider":"1800PetSupplies.com","version":"1.0","type":"link"}